Careers

Research Scientist, Immunology - Cancer Biology

Location: Cambridge, MA

POSITION

Kronos Bio seeks a highly motivated Research Scientist to join its drug discovery team located in Cambridge, MA. As a member of an interdisciplinary team, this individual will be expected to harness their strong background in immunology/immuno-oncology to help guide strategic scientific decisions and research program development. The applicant is expected to have a robust experimental skill set, an eagerness for learning, and contribute to a strong culture of teamwork and collaboration in a fast-paced environment.

ESSENTIAL FUNCTIONS AND DUTIES

  • Provide functional area expertise in immunology/immuno-oncology as a member of the Biology team.
  • Work within project teams and across functional groups to drive key elements of the discovery and preclinical development of novel cancer immunotherapies.
  • Independently design, optimize, and execute flow cytometry-based immunological assays to characterize lead compounds and their effects on anti-tumor immune responses.
  • Use a repertoire of in vitro assays (ELISA, qPCR, Nanostring, western blotting) to further define the MOI of lead molecules and the biology of novel targets.
  • Identify and implement new experimental techniques as required to answer critical scientific questions and advance programs.
  • Use literature survey to solve specific research problems.
  • Actively contribute to a focused, team-oriented atmosphere providing assistance and/or guidance to colleagues when needed.
  • Maintain high standards of laboratory safety and complete required training courses.
  • Perform research in compliance with all applicable regulatory and guidelines, as informed by supervisor.

SKILLS AND EXPERIENCE

  • PhD in immunology or related field with 0-2 years of industry or postdoctoral research experience (industry/biotech experience preferred).
  • Expertise in basic immunological techniques such as isolation and culture of primary cells, multi-color flow cytometry, and cytokine profiling.
  • Experience establishing ex vivo functional immune assays such as T cell proliferation, suppression, and cytotoxicity assays.
  • Extensive knowledge of T cell biology, including regulatory T cells, and mechanisms of immune suppression would be a plus.
  • Ability to work independently and able to balance multiple tasks or projects.
  • Diligent with details and timely execution and delivery of high-quality results.
  • Familiarity with analysis of genomic and gene expression data sets.
  • Highly analytical mind, attention to detail, organization skills, and rigorous experimental record keeping using an ELN system are critical.
  • Collaborative, proactive and optimistic personality.

To apply for this position, please forward your resume and cover letter to careers@kronosbio.com.